COPD Pathophysiology- things to know:

By JodonP วันศุกร์ที่ 5 ธันวาคม พ.ศ. 2557

     COPD is the chronic obstructive pulmonary disease and this is a highly progressive inflammatory disease that is connected to the lung parenchyma, airways and vasculature. The disease mainly damages and remodels the lung tissues and airways. Proper functioning of lung is hampered by the COPD. If this is left untreated for a long time then it results in various severe conditions such as heart failure or pulmonary hypertension. The actual pathophysiology of COPD is still undefined by the researchers.

     The inflammatory process of COPD is the driving aspect of its pathophysiology. A number of researches done by various researchers suggest that the inflammatory property of COPD results in various types of effects that include arrival of inflammatory cells like neutrophils, macrophages, lymphocytes etc. There are two main changes can be observed by the COPD and they are structural changes of lungs and thickened airways. Apart from that, smooth muscles and fibrosis can also be observed by COPD.

     The common reason for the development of COPD is smoking. Cigarette smoking mainly creates an inflammatory response to the lungs. This type of response does not stop at a position but it gradually grows for unlimited period of time. COPD can also be considered as an obstructive lung disease including the asthma, bronchitis, fibrosis etc. Destruction and degeneration of lung and other supporting tissues are two major characteristics of the COPD. This type of process can lead to the emphysema or sometime it can also cause chronic bronchitis. If the condition is severe then the patient can experience both of these diseases. Emphysema starts with very small obstruction in the airways and it can gradually progress and entirely block the airways present in the lungs.


     The COPD pathophysiology has not been understood totally by the researchers and doctors. Chronic inflammation of the linings in the cell plays a major role in the development of COPD. Smoking and some other inhaled irritants can also result in the narrowing of the airways in the lungs and it also results in hyperactivity. The airways in the lungs become narrow and the mucus production increases in COPD which leads to weakening the functions of cilia. Patients experience difficulties when clearing the secretions as the disease progress. Along with that, the patients develop a chronic productive cough, dyspnea and wheezing.

     The basic pathophysiology of COPD includes loss of elastic lining, increased resistance to the airflow and decreased expiratory flow. If the resistance to the airflow increases, the alveolar walls break quite frequently. In order to understand the COPD pathophysiology, it will be easier if you break the term into two parts. The first one is COPD and second one is pathophysiology. The meaning of pathophysiology is the changes that can be observed in the body during the disease.

    This term is not only limited to the COPD pathophysiology but it can be applied to other diseases as well. With the help of COPD pathophysiology, there are two things that can be determined. The first one is why the condition begins or what the main causes of the development of COPD are. If these two things can be understood then the people can be aware of it. The individuals can be educated with these things and the preventive measures can be easily taken. There might be sometimes when they cannot be avoided but by knowing more about the causes of COPD, the steps can be taken that can help in lessening the symptoms that might arise from COPD.

    The present medical science is focusing on the researches to find out the reasons and COPD pathophysiology but this should not be the only way to learn the conditions related to the COPD. One thing which is very important in medical science is keeping track of the progress of the patients and how they overcome the problems that are having. It might be positively or negatively but there is a need to observe the results thoroughly. It might be true that the effects of the treatment might not be same in all of the cases but they might vary a bit. Though, people can learn many things from it and they can stay away from those things that can cause the diseases like COPD.

     There are a number of researches going on to find out the main reasons of the COPD because this is one of the top five causes of death today. There are a number of researchers who are trying to find out more details on COPD and they are trying to find out the percentage of COPD sufferers among the total population.

     The researchers and physicians have been able to know varieties of things through the COPD pathophysiology. It includes the symptoms of COPD, the tests that are needed to be conducted in order to diagnose the COPD. It also includes levels of severity, possible treatments and prognosis. There are a number of treatment options available today for COPD and most of them seem to be effective. They can eventually decrease the development of COPD but there is no set treatment available that can treat COPD totally. A number of researches are going on to find out the more efficient treatment options for the COPD. In order to get rid of the problems of COPD the first thing which is needed to be done first is taking the preventive measures which can eliminate the formation of COPD.

    Two most important things often prescribed by the doctors are eating healthy and exercising daily. These two things help in reducing the negative health issues that are concerned with COPD. The COPD pathophysiology also says that not smoking is the most important thing for the patients with COPD. Other things which should be done to be treated from the COPD are minimizing the low quality air, getting a yearly flu etc and the most importantly, getting consults from a doctor.

    There are a number of websites available where you can find the COPD pathophysiology but it is important to go to a doctor as soon as you experience it.